Decoding the Development of Barrier Facilities for Laboratory Animals in China: From Inception to Ascendancy

2025.03.26

Barrier facilities for laboratory animals serve as a formidable fortress, safeguarding the health of laboratory animals, the accuracy of scientific research data, and the bottom line of biosafety. They play an irreplaceable and crucial role in the advancement of life science research. As a seasoned player in the purification equipment industry, Guangzhou Cleanroom Construction Co., Ltd. has always been in sync with the development of barrier facilities for laboratory animals in China. We have witnessed and propelled the booming development of this field. Now, let's review the development journey of barrier facilities for laboratory animals in China and explore their current construction status.
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I. Arduous Start: The Initial Stage (After the Founding of the People's Republic of China to the 1980s)

In the early days after the founding of the People's Republic of China, the laboratory animal industry in China was in its infancy. The facilities for breeding laboratory animals were extremely rudimentary. Take Ningxia Medical University as an example. The laboratory animal room established in 1958 consisted of merely several brick - and - tile houses, with an area of no more than 100 square meters. The equipment was limited to simple wooden cages and clay pots. The breeding methods were simple and extensive, and there was no effective control over the quality of laboratory animals. The facilities mainly met the basic teaching needs. During this period, due to a lack of both technology and funds, the construction of barrier facilities for laboratory animals was almost non - existent. The living environment of laboratory animals could not be effectively guaranteed, which severely restricted the development of life science research in China.

II. Forge Ahead: The Stage of Standardized Development (From the 1980s to the Early 21st Century)

In 1988, the Regulations on the Administration of Laboratory Animals promulgated by the Ministry of Science and Technology, like a guiding light, illuminated the path for the construction of laboratory animal facilities in China, providing important legal basis and regulatory guidance. In 1994, the national standard “Environment and Facilities for Laboratory Animals” was issued in China. The environmental facilities for laboratory animals were classified into four categories: open systems, sub - barrier systems, barrier systems, and isolation systems. This initiative strongly promoted the standardization process of facility construction.
Many universities and research institutions actively responded and increased their investment to build barrier facilities that met the standards. Soochow University is a typical example. During this period, it gradually improved its laboratory animal breeding and animal experiment facilities, constructing a 1500 - square - meter SPF - level barrier facility for laboratory animals. It also obtained the relevant license issued by the Jiangsu Laboratory Animal Management Committee, providing better experimental conditions for teaching and research work. Meanwhile, Guangzhou Cleanroom Construction Co., Ltd. keenly seized the opportunity of industry development, focusing on the research, development, and production of purification equipment. We provided essential equipment support for the construction of barrier facilities for laboratory animals, helping the industry move towards standardization.

III. Leap - forward Development: The Stage of Rapid Advancement (Since the Early 21st Century)

Entering the 21st century, life science research in China has entered a golden age of rapid development. International cooperation has become increasingly frequent, putting forward higher requirements for the construction of barrier facilities for laboratory animals. The state has increased its investment in the construction of laboratory animal facilities, and a batch of modern laboratory animal centers have emerged like mushrooms after rain.
The construction project of the Animal Experiment Platform of South China University of Technology was initiated in 2016 and completed successfully in 2017. Its barrier - level laboratory animal facilities were constructed in strict accordance with the national standard GB2010 - 14925 for laboratory animal facilities in China. It is equipped with an advanced intelligent control and management system that can automatically control parameters such as temperature, humidity, and pressure difference. The system can also automatically record, collect, and store relevant data, providing precise and stable experimental conditions for animal experiments.
In terms of laboratory animal welfare, China has been constantly exploring and improving. In 2006, the Guiding Opinions on Treating Laboratory Animals Kindly were officially issued, prompting the construction of facilities to pay more attention to animal welfare. This led to the optimization of animal cage designs and the improvement of the breeding environment. Relying on years of technical accumulation and innovative spirit, Guangzhou Cleanroom Construction Co., Ltd. has developed a series of high - efficiency and energy - saving purification equipment. These products are widely applied in the construction of barrier facilities for laboratory animals, significantly enhancing the purification level and operational efficiency of the facilities. We have contributed to creating a better living environment for laboratory animals.

IV. Booming Development: The Current Construction Status

Today, remarkable achievements have been made in the construction of barrier facilities for laboratory animals in China. More and more universities, research institutions, and enterprises have established modern laboratory animal centers. The scale of these facilities continues to expand, and their functions are constantly being improved. Geographically, regions along the eastern coast and cities rich in scientific research resources, such as Beijing, Shanghai, and Guangzhou, lead the country in the construction of such facilities, thanks to their strong scientific research capabilities and financial support. These facilities can not only fully meet domestic research needs but also play an important role in international cooperation.
Technologically, China's technologies in air purification, environmental control, and laboratory animal welfare protection have gradually approached international advanced levels. However, there is still room for improvement in some high - end equipment and key technologies. With the continuous attention of the state to life science research and the strong promotion of relevant policies, the construction of barrier facilities for laboratory animals will embrace broader development prospects. Guangzhou Cleanroom Construction Co., Ltd. will continue to uphold the spirit of innovation, increase investment in research and development, and provide more high - quality and efficient purification equipment and integrated solutions for the construction of barrier facilities for laboratory animals in China. We aim to promote the sustainable and healthy development of the industry.
The development journey of barrier facilities for laboratory animals in China is a struggle history full of hard work and innovation. It witnesses the continuous progress of life science research in China. Looking ahead, with the rapid development of science and technology and the deepening of international exchanges, the construction of barrier facilities for laboratory animals in China is bound to reach new heights, providing more solid support for life science research.
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