In the journey of life science exploration, animal laboratories serve as indispensable front - line bases. Barrier facilities in animal laboratories, acting as crucial defenses to protect the safety of experimental animals, researchers, and the external environment, are of great significance for the smooth progress of scientific research and the safeguarding of biosafety. Guangzhou Cleanroom Construction Co., Ltd., a seasoned player in the purification equipment industry, has always closely followed and implemented relevant regulations and standards, contributing to the creation of compliant and high - quality animal laboratory environments. Now, let's uncover the mystery of the regulations and standards for the construction of barrier facilities in Chinese animal laboratories.

The regulations and standards for barrier facilities in animal laboratories are not created out of thin air. Instead, they are the crystallization of the wisdom of countless experts, scholars, and practitioners. From the perspective of experimental animals, facilities that meet the standards provide them with a comfortable living space, reducing the impact of environmental stress on their physiology and behavior. This effectively ensures animal welfare and, in turn, improves the reliability and scientific nature of experimental data. From the aspect of public health security, well - regulated barrier facilities are like a sturdy shield, effectively blocking the spread of pathogens carried by experimental animals to the outside world, reducing the risk of infectious diseases, and safeguarding human health and ecological balance. Moreover, the regulations and standards meticulously regulate every aspect of facility construction, providing clear guidelines from project planning to specific construction, thus ensuring the orderly development of the industry.

Precise Regulation of Environmental Parameters: Temperature and humidity significantly affect the health of experimental animals and the results of experiments. This standard sets the temperature range at 20°C - 26°C and the relative humidity at 40% - 70%, ensuring that experimental animals are always in a suitable environment. For example, when breeding mice that are sensitive to temperature and humidity, a stable environment can minimize their physiological fluctuations and enhance the stability of experimental data.

Strict Control of Air Systems: A ventilation rate of 10 - 20 times per hour ensures the freshness and cleanliness of the air in the laboratory. Appropriate air velocity and a pressure difference of 10 - 15Pa between adjacent areas effectively prevent air cross - contamination between different regions. Additionally, a Class 10,000 air cleanliness level and strict control of the concentration of sedimentary bacteria create a clean breathing environment for experimental animals.

Scientific Setting of Other Indicators: A noise limit of less than 60dB(A) avoids stress interference on experimental animals caused by noise. A working illumination of 150 - 300lx meets the needs of experimental operations, while the animal - specific illumination that suits the physiological characteristics of animals helps maintain their normal physiological rhythms.

Risk Avoidance in Site Selection and Layout: The site selection of animal biosafety laboratories should be far away from natural epidemic foci, flammable, explosive, and other high - risk areas. The internal area is reasonably divided into clean areas, semi - contaminated areas, and contaminated areas. Through clear functional area division, the risk of cross - contamination between different areas is reduced.

Fortifying the Defense of Enclosure Structures: The good airtightness of doors and windows effectively prevents air leakage and the intrusion of pollutants. The walls, floors, and ceilings are made of corrosion - resistant and easy - to - clean materials, which not only facilitate daily maintenance but also reduce the possibility of microbial growth.

Pollution Prevention in Air Conditioning and Purification: The air conditioning system is reasonably divided to avoid air cross - contamination between different areas. At the same time, exhaust gas emissions must strictly comply with environmental protection standards to prevent pollution to the external environment.

Ensuring Safety through Airflow Organization: The design of airflow from clean areas to contaminated areas effectively prevents the reverse spread of pollutants. The up - supply and down - exhaust airflow organization method, along with the reasonable layout of air supply and exhaust outlets, ensures the stability of the airflow in the laboratory and reduces airflow dead zones.

Collaborative Coordination of Other Systems: The drinking water for animals in barrier environments needs to be sterilized to ensure water quality safety. The selection of water supply and drainage pipes should meet the requirements of corrosion resistance and no leaching to prevent pollution to the experimental environment. The electrical system should be powered at no less than Level - 2 load to ensure the continuous and stable operation of the laboratory.

The development of this standard aims to further standardize the acceptance of barrier facilities for laboratory animals. It will define the scope, content, rules, and scoring system of acceptance, providing a scientific and objective evaluation basis for the quality of facility construction and promoting the overall quality improvement of the industry.

In the construction of barrier facilities for animal laboratories, Guangzhou Cleanroom Construction Co., Ltd. strictly adheres to relevant regulations and standards. During the research and development process, the company optimizes products such as air showers and pass - through windows, regulates wind speed and shower time, improves sealing performance, and uses environmentally friendly materials. During the project implementation phase, every step, from site selection evaluation to layout design, equipment installation, and debugging, is strictly in line with the standards. The company also regularly organizes employees to study the updated content of regulations and standards and integrates them into products and projects.

With the development of science, technology, and society, the regulations and standards for the construction of barrier facilities in animal laboratories will continue to evolve. In terms of sustainable development, more stringent requirements will be imposed on energy consumption and carbon emissions, driving the industry towards a low - carbon and energy - saving transformation. In the field of intelligence, real - time monitoring and regulation of environmental parameters and equipment status will be achieved through the Internet of Things and big data, improving management efficiency and security. In terms of international integration, China will draw on international experience to align its regulations and standards with international ones, enhancing its international competitiveness in the field of life sciences.

The regulations and standards for the construction of barrier facilities in animal laboratories are important cornerstones for ensuring the healthy development of scientific research and biosafety. Guangzhou Cleanroom Construction Co., Ltd. will, as always, adhere to standards, continuously innovate, and contribute to the development of the industry. At the same time, we call on all parties in the industry to take joint action, attach importance to regulations and standards, and work together to create a safer, more efficient, and greener animal laboratory environment.