In the era of rapid technological development nowadays, clean laboratories play a crucial role in numerous fields such as biomedicine, electronic chip manufacturing, and scientific research experiments. Guangzhou Cleanroom Construction Co., Ltd., as a professional enterprise in the industry, is well aware of the importance of these technical parameters for laboratory performance. Today, we will introduce in detail the reference for the main technical parameter indexes of clean laboratories for you.

Cleanliness is a key indicator for measuring the air quality of clean laboratories. It is usually classified according to the concentration of suspended particles in the air, such as the common ISO 14644-1 standard. Generally speaking, in fields with stringent environmental requirements like biomedical research and development and high-precision electronic manufacturing, a cleanliness level of ISO 5 (Class 100) or even higher may be required, which means that the number of particles with a size greater than or equal to 0.5 micrometers per cubic meter of air should not exceed 100. In some general scientific research laboratories with relatively lower environmental requirements, ISO 7 (Class 10,000) or ISO 8 (Class 100,000) can also meet the basic needs. Different cleanliness levels directly affect the accuracy of experimental results and the stability of product quality. Therefore, when constructing clean laboratories, it is necessary to accurately determine the cleanliness level according to the actual usage requirements and achieve and maintain the corresponding cleanliness through advanced filtering equipment such as high-efficiency particulate air filters (HEPA) and ultra-low penetration air filters (ULPA).

Appropriate temperature and humidity are of vital importance for the normal operation of experimental equipment, the stability of experimental samples, and the comfort of operators. In most clean laboratories, the temperature is controlled within the range of 20 °C - 26 °C, and the humidity is controlled within 40% - 60% relative humidity (RH). In electronic chip manufacturing laboratories, excessive humidity may cause electronic components to get damp and short-circuit, while drastic fluctuations in temperature may affect the precision and performance of chips. In biomedical laboratories, unstable temperature and humidity may lead to the failure of cell culture or affect the active ingredients of drugs. To achieve precise temperature and humidity control, professional air-conditioning systems, such as constant temperature and humidity units, are usually adopted. Combined with humidity sensors, temperature sensors, and advanced control systems, they can monitor and adjust the indoor temperature and humidity in real time to ensure that they are always within the set ideal range.

The air change rate refers to the number of times that the indoor air is replaced by outdoor fresh air per unit time. It is closely related to factors such as cleanliness, indoor personnel density, and equipment heat generation. Generally, the air change rate of an ISO 5 clean laboratory may be as high as 200 - 400 times per hour, while that of an ISO 8 laboratory is relatively low, about 10 - 20 times per hour. A higher air change rate helps to quickly discharge indoor pollutants and heat, maintaining good air quality and temperature balance. However, it will also increase energy consumption and equipment costs. Therefore, when designing clean laboratories, it is necessary to comprehensively consider various factors, conduct precise calculations and simulations, and determine the most reasonable air change rate to achieve the best balance between performance and cost.

Clean laboratories usually need to maintain a certain pressure gradient to prevent the intrusion of external polluted air and ensure the directional flow of clean air inside. Generally, they are divided into positive pressure and negative pressure laboratories. Positive pressure laboratories are suitable for experimental areas with high environmental requirements and no biological hazards, such as electronic laboratories and precision instrument laboratories. The indoor pressure is usually 10 - 20 Pa higher than that of adjacent non-clean areas. Negative pressure laboratories are mainly used for experimental sites dealing with biological hazards or toxic and harmful substances, such as biosafety laboratories and chemical laboratories. The indoor pressure is relatively low to prevent harmful substances from leaking into the external environment and is generally 10 - 20 Pa lower than that of adjacent areas. Pressure control is achieved by pressure sensors installed on walls or ceilings for real-time monitoring and is precisely adjusted by fans, dampers, and other equipment to ensure the stability of the pressure gradient.

Sufficient and uniform illuminance is essential for operators to conduct fine operations and observations in the laboratory. Generally, the illuminance requirement of clean laboratories is between 300 - 500 lux, and glare and shadows that may interfere with experimental work should be avoided. Meanwhile, to create a quiet and comfortable working environment, noise control is also an indicator that cannot be ignored. The noise level in the laboratory should usually be controlled below 60 dB(A). By using low-noise equipment, reasonable layout, and effective sound insulation measures, such as the use of sound-absorbing materials and shock absorption treatment of equipment, the indoor noise can be reduced to ensure that operators can concentrate on experimental work without being disturbed by the outside world.

In conclusion, the various technical parameter indexes of clean laboratories are interrelated and interact with each other, jointly forming a complex and sophisticated environmental control system. Guangzhou Cleanroom Construction Co., Ltd., with its rich industry experience and professional technical team, can provide customers with a full range of clean laboratory solutions. From design and planning to equipment selection and installation, and then to later commissioning and maintenance, we strictly control every technical parameter to ensure that the laboratory performance reaches the international leading level, meets the experimental needs of customers in different fields, and provides a solid and reliable foundation for scientific research and industrial development.

If you have any questions about the construction of clean laboratories or related technical parameters, please feel free to contact us. Guangzhou Cleanroom Construction Co., Ltd. will serve you wholeheartedly!