Methods for Improving the Cleanliness of Bio-lab Purification Projects
2024.11.22
In the field of biological science research, the cleanliness of laboratories is directly related to the accuracy and reliability of experimental results as well as the safety of laboratory personnel. Guangzhou Kunling Purification Equipment Co., Ltd. has been focusing on the field of purification projects for many years and has provided high-quality purification solutions for numerous bio-labs. Today, we will share some effective methods for improving the cleanliness of bio-lab purification projects.
I. Rational Layout Planning
The layout of a bio-lab should be scientifically designed according to the experimental process and functional requirements.
· Clear Zoning: Strictly divide the clean area, semi-contaminated area, and contaminated area. For example, set up the reagent preparation area and sample processing area in the clean area, and separate them from the contaminated area by using dedicated passages to avoid cross-contamination. In the laboratories of some large biopharmaceutical enterprises, physical partitions and access control systems are set up to effectively control the flow of personnel and items in different areas.
· Optimization of Airflow Organization: Design a reasonable air flow direction to ensure that fresh air flows from the clean area to the contaminated area and then is discharged outdoors. Generally, the methods of supplying air from the top and exhausting from the bottom or supplying and exhausting from the sides are adopted to make the air flow evenly distributed and reduce vortices and dead corners. When planning the layout, sufficient space should be reserved for the installation of air supply outlets, exhaust outlets, and purification equipment to ensure the smooth circulation of air flow.
II. Selection of High-Quality Purification Equipment
· High-Efficiency Particulate Air (HEPA) Filters: These are the key equipment for bio-lab purification, which can filter out tiny particles, microorganisms and other pollutants in the air. Select appropriate efficiency HEPA filters according to the cleanliness level requirements of the laboratory. For example, for a Class 100 clean laboratory, H13 or H14 level HEPA filters should be chosen. Regularly inspect and replace the filters to ensure that their filtering effect remains in good condition all the time.
· Purification Air Conditioning System: It provides stable temperature and humidity control as well as air purification functions. Choose an air conditioning unit with good adjustment performance and energy-saving effect, which can accurately adjust the temperature, humidity and air supply volume according to the actual needs of the laboratory. Meanwhile, the ducts of the air conditioning system should be made of materials with good sealing performance and that are not easy to accumulate dust, and they should be cleaned and disinfected regularly.
III. Strict Personnel Management
· Training and Education: Conduct professional purification knowledge training for personnel entering the laboratory, including the importance of laboratory cleanliness, operating procedures, personal protection, etc. For example, teach laboratory personnel to correctly wear protective clothing, masks, gloves and other protective articles to avoid bringing external pollutants into the laboratory.
· Code of Conduct: Formulate strict personnel behavior guidelines, restrict unnecessary activities of personnel in the laboratory, such as prohibiting eating, smoking, and making loud noises in the laboratory. Require laboratory personnel to conduct experimental operations according to the prescribed procedures to reduce the impact of human factors on the cleanliness.
IV. Purification Treatment of Materials and Equipment
· Management of Material Entry: All materials entering the laboratory should undergo strict cleaning and disinfection treatments. For some raw materials and reagents that may carry pollutants, a special pre-treatment area can be set up outside the laboratory, and preliminary purification methods such as wiping, ultraviolet irradiation, and fumigation can be adopted. Then, through facilities such as transfer windows or airlocks, the materials can be transferred into the laboratory without destroying the laboratory's cleanliness.
· Equipment Cleaning and Maintenance: The equipment in the laboratory should be cleaned and maintained regularly, especially the parts that directly contact experimental samples. For some large equipment, such as centrifuges and incubators, local purification devices can be installed inside the equipment to reduce the impact of pollutants generated during the operation of the equipment on the laboratory environment.
V. Environmental Monitoring and Maintenance
· Real-Time Monitoring System: Install monitoring equipment such as dust particle counters and microorganism samplers to conduct real-time monitoring of the laboratory's cleanliness. Set reasonable alarm thresholds, and when the cleanliness indicators exceed the specified range, send out alarms in time so that corresponding measures can be taken for adjustment.
· Regular Cleaning and Disinfection: Formulate a regular cleaning and disinfection plan to conduct comprehensive cleaning and disinfection on the laboratory floor, walls, laboratory benches, equipment surfaces, etc. Adopt appropriate disinfectants and disinfection methods to ensure the disinfection effect while not causing harm to experimental equipment and personnel. For example, chlorine-containing disinfectants can be used to wipe and disinfect the floor, and ultraviolet lamps can be used to irradiate and disinfect the laboratory benches.
Through the comprehensive application of the above measures, the cleanliness of bio-lab purification projects can be effectively improved, providing a safe, reliable and stable experimental environment for biological science research. Guangzhou Kunling Purification Equipment Co., Ltd. will continue to be committed to the research and development and innovation of purification technologies, and provide higher-quality products and services for bio-lab purification projects.
Contact
Leave your information and we will contact you.